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Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment

機譯:心臟植入電子設備感染;提取和抗生素治療后的長期結果

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摘要

Background: The aim of the study was to examine the treatment outcome for patients with cardiovascular implantable electronic device (CIED) infections after extraction. Methods: Patients who underwent CIED extractions due to an infection at Karolinska University Hospital 2006–2015 were analyzed. Results: In total, 165 patients were reviewed, 104 (63%) with pocket infection and 61 (37%) with systemic infection. Of the patients with systemic infection, 34 and 25 patients fulfilled the criteria for definite and possible endocarditis, respectively. Complications after extraction occurred only in one patient. Reimplantation was made after a mean of 9.5 days and performed in 81% of those with pocket infection and 44.3% in systemic infection. Infection with the new device occurred in 4.6%. The mean length of hospital stay for patients with pocket infection was 5.7 days, compared to 38.6 days in systemic infection. One-year mortality was 7.7% and 22.2% in pocket infection and systemic infection, respectively. Patients with Staphylococcus aureus infection had a higher mortality. Conclusions: In this study, the majority of the patients had a pocket CIED infection, with a short hospital stay. Patients with a systemic infection, and S. aureus etiology, had a prolonged hospital stay and a higher mortality.
機譯:背景:該研究的目的是檢查提取后心血管植入電子設備(CIED)感染患者的治療結果。方法:分析了2006 - 2015年Karolinska大學醫院感染導致的患者的患者。結果:總共綜述165名患者,104名(63%),口袋感染和61(37%),具有全身感染。對系統性感染的患者,34例和25名患者分別滿足了明確和可能的心內膜炎的標準。提取后的并發癥僅在一個患者中發生。在均值9.5天后進行再植入,并以81%的人在口袋感染中進行,系統感染44.3%。用新設備感染于4.6%。口袋感染患者的住院住院的平均長度為5.7天,相比于38.6天內的全身感染。口袋感染和全身性感染分別為每年死亡率為7.7%和22.2%。金黃色葡萄球菌感染患者具有較高的死亡率。結論:在這項研究中,大多數患者患有口袋的感染,住院時間短暫。患有全身感染的患者和金黃色葡萄球病因,延長了住院,死亡率較高。

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