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Bio-integrated electronics and sensor systems

機譯：生物集成電子和傳感器系統

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Skin-mounted epidermal electronics, a strategy for bio-integrated electronics, provide an avenue to non-invasive monitoring of clinically relevant physiological signals for healthcare applications. Current conventional systems consist of single-point sensors fastened to the skin with adhesives, and sometimes with conducting gels, which limits their use outside of clinical settings due to loss of adhesion and irritation to the user. In order to facilitate extended use of skin-mounted healthcare sensors without disrupting everyday life, we envision electronic monitoring systems that integrate seamlessly with the skin below the notice of the user. This manuscript reviews recent significant results towards our goal of wearable electronic sensor systems for long-term monitoring of physiological signals. Ultra-thin epidermal electronic systems (EES) are demonstrated for extended use on the skin, in a conformal manner, including during everyday bathing and sleeping activities. We describe the assessment of clinically relevant physiological parameters, such as electrocardiograms (ECG), electromyograms (EMG), electroencephalograms (EEG), temperature, mechanical strain and thermal conductivity, using examples of multifunctional EES devices. Additionally, we demonstrate capability for real life application of EES by monitoring the system functionality, which has no discernible change, during cyclic fatigue testing.
機譯：皮膚安裝的表皮電子設備是生物集成電子設備的一種策略，為醫療應用中臨床相關生理信號的無創監測提供了途徑。當前的常規系統包括通過粘合劑，有時使用導電凝膠固定在皮膚上的單點傳感器，由于失去了附著力和對用戶的刺激，其在臨床環境之外的使用受到限制。為了促進在皮膚上安裝醫療傳感器的廣泛使用而又不影響日常生活，我們構想了電子監控系統，可在用戶注意的情況下與皮膚無縫集成。本手稿回顧了可實現長期監測生理信號的可穿戴電子傳感器系統目標的近期重大成果。超薄表皮電子系統（EES）已被證明可以以保形方式在皮膚上廣泛使用，包括在日常沐浴和睡眠活動中使用。我們以多功能EES設備為例，介紹對臨床相關生理參數的評估，例如心電圖（ECG），肌電圖（EMG），腦電圖（EEG），溫度，機械應變和熱導率。此外，在循環疲勞測試過程中，我們通過監視沒有明顯變化的系統功能來證明EES在現實生活中的應用能力。

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  • 會議地點 Baltimore MD(US)
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    Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States;

    Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States;

    Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States;

    Department of Mechanical engineering, Pohang University of Science and Technology, Pohang, 790-784, Republic of Korea;

    Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States;

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